Title : Kinetics of interaction of Rab5 and Rab7 with nucleotides and magnesium ions.

Pub. Date : 1996 Aug 23

PMID : 8702787






2 Functional Relationships(s)
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1 As with the small GTP-binding protein Ha-Ras p21 and with EF-Tu, nucleotide binding occurs in at least two steps and is describable in terms of a relatively weak initial interaction followed by a highly irreversible isomerization of the protein-nucleotide complex, which results in a change in the fluorescence properties. Guanosine Triphosphate H3 histone pseudogene 16 Homo sapiens
2 The results demonstrate a high degree of mechanistic similarity between the Rab proteins and other GTP-binding proteins, which have been examined in detail, including Ha-Ras p21, Ran, and EF-Tu. Guanosine Triphosphate H3 histone pseudogene 16 Homo sapiens