Title : Metabolism of the immunosuppressant tacrolimus in the small intestine: cytochrome P450, drug interactions, and interindividual variability.

Pub. Date : 1995 Dec

PMID : 8689938






1 Functional Relationships(s)
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1 The metabolism of tacrolimus by human small intestine was inhibited by anti-CYP3A, troleandomycin, and erythromycin, indicating that, as in the liver, CYP3A enzymes are the major enzymes for tacrolimus metabolism in the human small intestine. Troleandomycin cytochrome P450 family 3 subfamily A member 4 Homo sapiens