Title : Recombinant human stem cell factor (kit ligand) promotes human mast cell and melanocyte hyperplasia and functional activation in vivo.

Pub. Date : 1996 Jun 1

PMID : 8676090






1 Functional Relationships(s)
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1 A 14-d course of r-hSCF significantly increased dermal mast cell density at sites distant to those injected with the cytokine and also increased both urinary levels of the major histamine metabolite, methyl-histamine, and serum levels of mast cell alpha-tryptase. Methylhistamines KIT ligand Homo sapiens