Pub. Date : 1996 Apr
PMID : 8671854
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cuprophane haemodialysis induces upregulation of LPS receptor (CD14) on monocytes: role of complement activation. | cuprammonium cellulose | CD14 molecule | Homo sapiens |
| 2 | RESULTS: In vitro haemodialysis of whole blood from healthy volunteers on cuprophane membrane resulted within 30 min in upregulation of monocyte CD14 expression. | cuprammonium cellulose | CD14 molecule | Homo sapiens |
| 3 | The reuse of the cuprophane membrane abolished both complement activation and CD14 upregulation. | cuprammonium cellulose | CD14 molecule | Homo sapiens |
| 4 | Moreover, incubation of whole blood with recombinant C5a led to an increased monocyte CD14 expression supporting a role for complement activation in the rapid cuprophane-induced CD14 upregulation. | cuprammonium cellulose | CD14 molecule | Homo sapiens |
| 5 | Moreover, incubation of whole blood with recombinant C5a led to an increased monocyte CD14 expression supporting a role for complement activation in the rapid cuprophane-induced CD14 upregulation. | cuprammonium cellulose | CD14 molecule | Homo sapiens |
| 6 | In vivo dialysis on cuprophane membrane also resulted in early monocyte CD14 upregulation as indicated by higher CD14 expression found after 60 min on monocytes obtained from the efferent as compared to the afferent line of the dialyser, a phenomenon that was not observed during haemodialysis on AN69 membrane. | cuprammonium cellulose | CD14 molecule | Homo sapiens |
| 7 | In vivo dialysis on cuprophane membrane also resulted in early monocyte CD14 upregulation as indicated by higher CD14 expression found after 60 min on monocytes obtained from the efferent as compared to the afferent line of the dialyser, a phenomenon that was not observed during haemodialysis on AN69 membrane. | cuprammonium cellulose | CD14 molecule | Homo sapiens |
| 8 | CONCLUSION: Haemodialysis on the complement-activating cuprophane membrane induces the rapid upregulation of the CD14 LPS-receptor on monocytes. | cuprammonium cellulose | CD14 molecule | Homo sapiens |