Title : Identification of 14-3-3 proteins in human platelets: effects of synthetic peptides on protein kinase C activation.

Pub. Date : 1996 Apr 1

PMID : 8670130






1 Functional Relationships(s)
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1 In washed, saponin-permeabilized platelets incubated with [gamma-32P]ATP, thrombin- and phorbol 12-myristate 13-acetate (PMA)-induced phosphorylation of several proteins (66, 45, and 20kDa) was inhibited by preincubation with AS peptide (KNVVGARRSSWRVISSIEQK) based on the pseudosubstrate-like region of the 14-3-3 family. Saponins coagulation factor II, thrombin Homo sapiens