Title : RO 31-8220, a novel protein kinase C inhibitor, inhibits early and late T cell activation events.

Pub. Date : 1996 Jun 15

PMID : 8669110






1 Functional Relationships(s)
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1 Noninhibitory doses of CsA (8 nM) or FK506 (0.2 nM) suppressed mitogen-induced IL-2 production by 60-80% when combined with a noninhibitory dose (25 nM) of Ro 31-8220, indicating the potent synergy between these agents. Tacrolimus interleukin 2 Homo sapiens