Pub. Date : 1996 Mar 15
PMID : 8665918
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Bradykinin induces tyrosine phosphorylation in human foreskin fibroblasts and 293 cells transfected with rat B2 kinin receptor. | Tyrosine | kininogen 1 | Homo sapiens |
| 2 | We studied whether in human foreskin fibroblasts bradykinin treatment induces tyrosine phosphorylation of cellular proteins. | Tyrosine | kininogen 1 | Homo sapiens |
| 3 | The effect evoked by 10 nM bradykinin was rapid (2 min) and it was partially reduced by the B2-kinin-receptor antagonist Hoe 140 which was shown to be a weak inducer of tyrosine phosphorylation. | Tyrosine | kininogen 1 | Homo sapiens |
| 4 | The bradykinin-mediated tyrosine phosphorylation events were reproduced in human embryonal kidney 293 fibroblasts which were transiently transfected with the rat B2 kinin receptor, but they were not observed in untransfected 293 control cells. | Tyrosine | kininogen 1 | Homo sapiens |
| 5 | While IGF-I, insulin and EGF were almost ineffective, PDGF stimulated the tyrosine phosphorylation of 130-kDa bands with a similar pattern to that produced by bradykinin. | Tyrosine | kininogen 1 | Homo sapiens |