Title : Regulation of interleukin-8 gene expression by interleukin-1beta, osteotropic hormones, and protein kinase inhibitors in normal human bone marrow stromal cells.

Pub. Date : 1996 Jul 12

PMID : 8663179






1 Functional Relationships(s)
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1 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine, HCl (50 microM) and staurosporine (1 microM), potent inhibitors of protein kinase C, and genistein (100 microM), a specific protein tyrosine kinase inhibitor blocked IL-1beta-induced IL-8 gene expression. 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine interleukin 1 beta Homo sapiens