Title : Correlation of chloroethylnitrosourea resistance with ERCC-2 expression in human tumor cell lines as determined by quantitative competitive polymerase chain reaction.

Pub. Date : 1996 Jun 1

PMID : 8653679






1 Functional Relationships(s)
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Protein Name
Organism
1 Normalized ERCC-2 gene expression (either to beta-actin or to total RNA) correlates with cytotoxicity of 1,3-bis-(2-chloroethyl)-1-nitrosourea or (2-chloroethyl)-3-sarcosinamide-1-nitrosourea, suggesting that ERCC-2 may play an important role in drug resistance in these cell lines. 2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide POTE ankyrin domain family member F Homo sapiens