Title : Histamine inhibits tumor necrosis factor alpha release by mast cells through H2 and H3 receptors.

Pub. Date : 1996 Jun

PMID : 8652190






2 Functional Relationships(s)
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1 Furthermore, blockage of H2 receptors with ranitidine increased the release of TNF alpha from PMC stimulated with antigen, suggesting that histamine released by MC within 10 min of antigen stimulation downregulates the subsequent release of TNF alpha from the same MC population. Ranitidine tumor necrosis factor Rattus norvegicus
2 Furthermore, blockage of H2 receptors with ranitidine increased the release of TNF alpha from PMC stimulated with antigen, suggesting that histamine released by MC within 10 min of antigen stimulation downregulates the subsequent release of TNF alpha from the same MC population. Ranitidine tumor necrosis factor Rattus norvegicus