Pub. Date : 1996 Mar 21
PMID : 8649819
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Identification and cloning of EI24, a gene induced by p53 in etoposide-treated cells. | Etoposide | transformation related protein 53, pseudogene | Mus musculus |
| 2 | To search for candidate genes involved in p53-mediated apoptosis, the differential display technique was used to identify RNA species whose expression was altered in murine NIH3T3 cells treated with the cytotoxic drug etoposide. | Etoposide | transformation related protein 53, pseudogene | Mus musculus |
| 3 | Induction of EI24 mRNA by etoposide required expression of wild-type p53 in murine embryonic fibroblasts which had been transformed with the oncogenes E1A and T24 H-ras; and overexpression of functional p53 in these cells was sufficient to induce expression of the EI24 mRNA. | Etoposide | transformation related protein 53, pseudogene | Mus musculus |
| 4 | Induction of EI24 mRNA by etoposide required expression of wild-type p53 in murine embryonic fibroblasts which had been transformed with the oncogenes E1A and T24 H-ras; and overexpression of functional p53 in these cells was sufficient to induce expression of the EI24 mRNA. | Etoposide | transformation related protein 53, pseudogene | Mus musculus |