Pub. Date : 1996 Jun 1
PMID : 8647935
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Immunosuppressant FK506 induces interleukin-6 production through the activation of transcription factor nuclear factor (NF)-kappa(B). | Tacrolimus | interleukin 6 | Homo sapiens |
| 2 | We further show that FK506 induces NF-kappaB-regulated IL-6 production in vitro and in vivo, in particular in kidney. | Tacrolimus | interleukin 6 | Homo sapiens |
| 3 | These results thus suggest a causal relationship between FK506-induced NF-kappaB activation/IL-6 production and some of FK506-induced renal abnormalities. | Tacrolimus | interleukin 6 | Homo sapiens |
| 4 | These results thus suggest a causal relationship between FK506-induced NF-kappaB activation/IL-6 production and some of FK506-induced renal abnormalities. | Tacrolimus | interleukin 6 | Homo sapiens |