Title : An ESR and spectrophotometric study of the denitration of nitroheterocyclic drugs by liver homogenates and their metabolic consumption by liver microsomes from cytochrome P-450-induced mice.

Pub. Date : 1996 Mar 25

PMID : 8646785






2 Functional Relationships(s)
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1 Pretreating mice with three inducers of cytochrome P-450 (phenobarbital, clophen A50 and butylated hydroxytoluene (BHT)) increased the yield of the nitrosyl complex which correlated with a rise in the cytochrome P-450 content of mouse liver microsomes. Phenobarbital cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus
2 Pretreating mice with three inducers of cytochrome P-450 (phenobarbital, clophen A50 and butylated hydroxytoluene (BHT)) increased the yield of the nitrosyl complex which correlated with a rise in the cytochrome P-450 content of mouse liver microsomes. Phenobarbital cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus