Title : Lack of cross talk between alpha1-adrenergic and angiotensin type 1 receptors in neurons of spontaneously hypertensive rat brain.

Pub. Date : 1996 Jun

PMID : 8641736






3 Functional Relationships(s)
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1 Norepinephrine causes downregulation of angiotensin II (Ang II) receptors in Wistar-Kyoto rat (WKY) brain neuronal cultures. Norepinephrine angiotensinogen Rattus norvegicus
2 Norepinephrine causes downregulation of angiotensin II (Ang II) receptors in Wistar-Kyoto rat (WKY) brain neuronal cultures. Norepinephrine angiotensinogen Rattus norvegicus
3 Thus, these data show that norepinephrine-mediated downregulation of AT1 receptors is associated with a parallel decrease in AT1 mRNA and Ang II stimulation of norepinephrine transporter mRNA and involves the alpha1a-adrenergic receptor in neurons of WKY brain. Norepinephrine angiotensinogen Rattus norvegicus