Title : High-dose melphalan and cyclophosphamide with autologous bone marrow rescue for recurrent/progressive malignant brain tumors in children: a pilot pediatric oncology group study.

Pub. Date : 1996 Feb

PMID : 8636747






1 Functional Relationships(s)
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1 PURPOSE: To determine the maximum-tolerated dose of cyclophosphamide (CTX) when administered sequentially with melphalan 60 mg/m2/d for 3 days, followed by autologous bone marrow rescue (ABMR), in children with recurrent or progressive malignant brain tumors, and to make preliminary observations on efficacy. Cyclophosphamide cytochrome P450 family 27 subfamily A member 1 Homo sapiens