Title : Repair-deficient 3-methyladenine DNA glycosylase homozygous mutant mouse cells have increased sensitivity to alkylation-induced chromosome damage and cell killing.

Pub. Date : 1996 Feb 15

PMID : 8631315






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The loss of Aag renders cells significantly more sensitive to methyl methanesulfonate-induced chromosome damage, and to cell killing induced by two methylating agents, one of which produces almost exclusively 3MeAs. Methyl Methanesulfonate N-methylpurine-DNA glycosylase Mus musculus