Pub. Date : 1996 Apr
PMID : 8623837
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | However, transforming growth factor-beta 1 inhibited forskolin-stimulated androstenedione production to near basal levels and increased progesterone 1.4- to 2-fold while suppressing P450c17 enzyme activity to near basal levels, but it did not affect 3 beta HSD activity. | Colforsin | transforming growth factor beta 1 | Homo sapiens |
| 2 | Forskolin-stimulated immunodetectable P450c17 alpha protein was markedly inhibited by transforming growth factor-beta 1. | Colforsin | transforming growth factor beta 1 | Homo sapiens |
| 3 | In addition, transforming growth factor-beta 1 markedly inhibited the forskolin-stimulation of P450c17 messenger ribonucleic acid, while not significantly altering P450scc or 3 beta HSD messenger ribonucleic acid expression. | Colforsin | transforming growth factor beta 1 | Homo sapiens |
| 4 | Transforming growth factor-beta 1 inhibited forskolin stimulation of androstenedione production through the inhibition of P450c17 expression. | Colforsin | transforming growth factor beta 1 | Homo sapiens |