Pub. Date : 1996 May 15
PMID : 8621938
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | An immunoblot analysis revealed that both ATPo and the cross-linking of FcRs led to tyrosine phosphorylation of 44- and 110-kDa proteins, which thus suggested that these tyrosine-phosphorylated proteins are involved in a modulation of the degranulation process following an elevation of [Ca2+]i. Pretreatment with PMA inhibited the FcR-induced [Ca2+]i increase, while not inhibiting the ATPo-induced one, thus suggesting that ATPo can mobilize [Ca2+]i even when protein kinase C (PKC) has already been activated. | Tetradecanoylphorbol Acetate | Fc receptor | Mus musculus |