Title : Thrombin stimulates wortmannin-inhibitable phosphoinositide 3-kinase and membrane blebbing in CHRF-288 cells.

Pub. Date : 1996 Mar 15

PMID : 8615773






2 Functional Relationships(s)
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1 We report that these cells, when exposed to thrombin or SFLLRN (the peptide Ser-Phe-Leu-Leu-Arg-Asn, a thrombin-receptor ligand) rapidly change shape, forming membrane "blebs", detectable by differential interference contrast or confocal microscopy, as well as labelled 3-phosphorylated phosphoinositides. Leucine coagulation factor II, thrombin Homo sapiens
2 We report that these cells, when exposed to thrombin or SFLLRN (the peptide Ser-Phe-Leu-Leu-Arg-Asn, a thrombin-receptor ligand) rapidly change shape, forming membrane "blebs", detectable by differential interference contrast or confocal microscopy, as well as labelled 3-phosphorylated phosphoinositides. Leucine coagulation factor II, thrombin Homo sapiens