Title : Fibrates induce mdr2 gene expression and biliary phospholipid secretion in the mouse.

Pub. Date : 1996 Mar 15

PMID : 8615769






1 Functional Relationships(s)
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1 Increased levels of mdr2 mRNA were observed in the liver of mice treated with different fibrates: ciprofibrate, 660+/-155% (as compared with control group); clofibrate, 611+/-77%; bezafibrate, 410+/-47%; fenofibrate, 310+/-52%; gemfibrozil, 190+/-25% (P <0.05 compared with control group). ciprofibrate ATP-binding cassette, sub-family B (MDR/TAP), member 4 Mus musculus