Pub. Date : 1996 Feb 15
PMID : 8611037
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CYP2C11 is the most abundant among the P450s present in untreated rat liver (approximately 50% of total P450) and is known for metabolizing testosterone mainly in positions 2 alpha and 16 alpha. | Testosterone | cytochrome P450, subfamily 2, polypeptide 11 | Rattus norvegicus |
| 2 | Testosterone-hydroxylating activities from CYP2C11 Gunn expressed in insect cells were decreased by 40% when compared to CYP2C11 Wistar, reflecting with a lesser extent the decrease we have previously reported in liver microsomes. | Testosterone | cytochrome P450, subfamily 2, polypeptide 11 | Rattus norvegicus |
| 3 | Testosterone-hydroxylating activities from CYP2C11 Gunn expressed in insect cells were decreased by 40% when compared to CYP2C11 Wistar, reflecting with a lesser extent the decrease we have previously reported in liver microsomes. | Testosterone | cytochrome P450, subfamily 2, polypeptide 11 | Rattus norvegicus |