Pub. Date : 1996 Apr 15
PMID : 8609406
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A carbohydrate structure associated with CD15 (Lewis x) on myeloid cells is a novel ligand for human CD2. | Carbohydrates | fucosyltransferase 4 | Homo sapiens |
| 2 | In this study we show that mAbs specific for the carbohydrate Ag Lewis x (CD15, Gal-beta 1-4 GlcNAc alpha 1-3Fuc) inhibit multimeric rCD2 binding to CD2L. | Carbohydrates | fucosyltransferase 4 | Homo sapiens |
| 3 | Thus, it is likely that CD2L is a carbohydrate structure closely associated with, yet distinct from, CD15, which can be sterically blocked by CD15 mAb. | Carbohydrates | fucosyltransferase 4 | Homo sapiens |
| 4 | Collectively, this study indicates that a CD15 (Lewis x)-associated carbohydrate structure(s), which has previously been shown to be a selectin ligand, also may function as an important CD2 ligand on myeloid cells. | Carbohydrates | fucosyltransferase 4 | Homo sapiens |