Title : Investigation of mechanism-based inhibitors of complement targeting the activated thioester of human C3.

Pub. Date : 1996 Mar 22

PMID : 8602875






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Activated C3b primarily forms ester bonds with hydroxyl groups of carbohydrates on complement activating surfaces, but it has also been shown to react with the hydroxyl group of tyrosine and with specific Ser and Thr residues on IgG and on complement protein C4b. Serine complement C3 Homo sapiens