Pub. Date : 1996 Mar 1
PMID : 8598312
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Involvement of MDR1 P-glycoprotein in multifactorial resistance to methotrexate. | Methotrexate | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | The MTX-selected sublines show increased expression and function of the MDR1 gene, based on the measurement of MDR1 mRNA, Pgp and rhodamine 123 accumulation. | Methotrexate | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | The MTX-selected sublines show increased expression and function of the MDR1 gene, based on the measurement of MDR1 mRNA, Pgp and rhodamine 123 accumulation. | Methotrexate | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | Sequence analysis of the MDR1 cDNA from MTX-selected CCRF-CEM cells revealed no mutations in the protein coding region. | Methotrexate | ATP binding cassette subfamily B member 1 | Homo sapiens |