Pub. Date : 1996 Apr
PMID : 8597960
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Aminoglycoside antibiotics restore CFTR function by overcoming premature stop mutations. | Aminoglycosides | CF transmembrane conductance regulator | Homo sapiens |
| 2 | Aminoglycoside treatment resulted in the expression of full-length CFTR and restored its cyclic AMP-activated chloride channel activity. | Aminoglycosides | CF transmembrane conductance regulator | Homo sapiens |
| 3 | Another aminoglycoside, gentamicin, also promoted the expression of full-length CFTR. | Aminoglycosides | CF transmembrane conductance regulator | Homo sapiens |
| 4 | These results suggest that treatment with aminoglycosides may provide a means of restoring CFTR function in patients with this class of mutation. | Aminoglycosides | CF transmembrane conductance regulator | Homo sapiens |