Title : cAMP enhances inducible nitric oxide synthase mRNA stability in cardiac myocytes.

Pub. Date : 1995 Dec

PMID : 8594915






3 Functional Relationships(s)
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1 Maximal nitrite (NO2(-)) production by cultured neonatal rat cardiac myocytes was achieved with 500 U/ml interleukin-1 beta (IL-1 beta) for 48 h (4.6 +/- 0.3 nmol/1.25 x 10(5) cells; n = 12). Nitrogen Dioxide interleukin 1 beta Rattus norvegicus
2 Maximal nitrite (NO2(-)) production by cultured neonatal rat cardiac myocytes was achieved with 500 U/ml interleukin-1 beta (IL-1 beta) for 48 h (4.6 +/- 0.3 nmol/1.25 x 10(5) cells; n = 12). Nitrogen Dioxide interleukin 1 beta Rattus norvegicus
3 The addition of FSK or DBcAMP to IL-1 beta significantly increased NO2-) levels vs. IL-1 beta alone (9.7 +/- 0.6 and 10.9 +/- 0.8 vs. 4.6 +/- 0.3 nmol/1.25 x 10(5) cells per 48 h, respectively; P < 0.01; n = 12). Nitrogen Dioxide interleukin 1 beta Rattus norvegicus