Title : Osteoclasts and transforming growth factor-beta: estrogen-mediated isoform-specific regulation of production.

Pub. Date : 1996 Feb

PMID : 8593810






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Although an E2 dose-dependent increase in TGF beta protein accumulation in osteoclast-conditioned medium was measured at 4 h of treatment, a steroid dose-dependent decrease in the accumulation of active TGF beta was measured after 18 h of estrogen treatment. Steroids transforming growth factor beta 1 Homo sapiens
2 The steroid specificity of the increased TGF beta accumulation was confirmed by demonstrating that the E2-induced increase in TGF beta protein levels in the medium was inhibited by cotreatment with a specific E2 antagonist. Steroids transforming growth factor beta 1 Homo sapiens
3 The steroid specificity of the increased TGF beta accumulation was confirmed by demonstrating that the E2-induced increase in TGF beta protein levels in the medium was inhibited by cotreatment with a specific E2 antagonist. Steroids transforming growth factor beta 1 Homo sapiens