Title : Phosphatidylcholine could be the source of 1,2-DAG which activates protein kinase C in EGF-stimulated colon carcinoma cells (HT29).

Pub. Date : 1995 Nov

PMID : 8593248






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Here we investigate the effect of well-known PKC activator 12-O-tetradecanoyl-2 phorbol-13-acetate (TPA), on the levels of 32P incorporation into EGF induced phosphatidylinositols (PI, PI4P, PI4, 5P2) and different phospholipids (PC, PA, PS) as well as on induced tyrosine kinase activity. Tetradecanoylphorbol Acetate epidermal growth factor Homo sapiens
2 TPA significantly decreased the effects of EGF and it had the biggest inhibitory effect on EGF induced PC level. Tetradecanoylphorbol Acetate epidermal growth factor Homo sapiens
3 TPA significantly decreased the effects of EGF and it had the biggest inhibitory effect on EGF induced PC level. Tetradecanoylphorbol Acetate epidermal growth factor Homo sapiens