Pub. Date : 1995 Dec
PMID : 8587236
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The objective of this study was to investigate the role of cAMP in the regulation of IL-6 and IL-8 gene expression and peptide production in IL-1 stimulated human MC. | Cyclic AMP | interleukin 1 alpha | Homo sapiens |
| 2 | Thus our data show that cAMP can potentiate IL-1 induced IL-6 production, while having no effect on IL-8 induction, and PGE2 may operate via a positive feedback loop to up-regulate IL-1 induced IL-6. | Cyclic AMP | interleukin 1 alpha | Homo sapiens |
| 3 | Taken together, our results demonstrate that cAMP differentially regulates IL-6 and IL-8 production in IL-1-stimulated human MC. | Cyclic AMP | interleukin 1 alpha | Homo sapiens |