Title : Augmentation of TNF cytotoxicity by protein kinase C inhibitors: role of arachidonic acid and manganese superoxide dismutase.

Pub. Date : 1995 Aug

PMID : 8580367






10 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The mechanism(s) of PKC inhibitor-mediated potentiation of the cytotoxic activity of TNF was investigated by analysing the effect of PKC inhibitors on TNF-induced arachidonic acid release in TNF-sensitive and -resistant cells. Arachidonic Acid tumor necrosis factor Homo sapiens
2 The mechanism(s) of PKC inhibitor-mediated potentiation of the cytotoxic activity of TNF was investigated by analysing the effect of PKC inhibitors on TNF-induced arachidonic acid release in TNF-sensitive and -resistant cells. Arachidonic Acid tumor necrosis factor Homo sapiens
3 The mechanism(s) of PKC inhibitor-mediated potentiation of the cytotoxic activity of TNF was investigated by analysing the effect of PKC inhibitors on TNF-induced arachidonic acid release in TNF-sensitive and -resistant cells. Arachidonic Acid tumor necrosis factor Homo sapiens
4 TNF induced the release of arachidonic acid in TNF-sensitive cells but had no effect in TNF-resistant cells. Arachidonic Acid tumor necrosis factor Homo sapiens
5 TNF induced the release of arachidonic acid in TNF-sensitive cells but had no effect in TNF-resistant cells. Arachidonic Acid tumor necrosis factor Homo sapiens
6 TNF induced the release of arachidonic acid in TNF-sensitive cells but had no effect in TNF-resistant cells. Arachidonic Acid tumor necrosis factor Homo sapiens
7 The combination of PKC inhibitor and TNF potentiated the release of arachidonic acid from TNF-sensitive cells, but failed to induce arachidonic acid release in TNF-resistant cells. Arachidonic Acid tumor necrosis factor Homo sapiens
8 The combination of PKC inhibitor and TNF potentiated the release of arachidonic acid from TNF-sensitive cells, but failed to induce arachidonic acid release in TNF-resistant cells. Arachidonic Acid tumor necrosis factor Homo sapiens
9 The combination of PKC inhibitor and TNF potentiated the release of arachidonic acid from TNF-sensitive cells, but failed to induce arachidonic acid release in TNF-resistant cells. Arachidonic Acid tumor necrosis factor Homo sapiens
10 Kinetic analysis of TNF-induced arachidonic acid release in CL8-1 melanoma cells revealed that it was an early event which preceded TNF tumour lytic activity. Arachidonic Acid tumor necrosis factor Homo sapiens