Title : FK506 and cyclosporin A inhibit granulocyte/macrophage colony-stimulating factor production by mononuclear cells in asthma.

Pub. Date : 1995 Sep

PMID : 8575571






3 Functional Relationships(s)
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1 FK506 and cyclosporin A inhibit granulocyte/macrophage colony-stimulating factor production by mononuclear cells in asthma. Tacrolimus colony stimulating factor 2 Homo sapiens
2 To assess this, we compared the inhibitory effects of FK506 and cyclosporin A on production of granulocyte/macrophage colony-stimulating factor and interleukin-5 by interleukin-2- or Dermatophagoides farinae-stimulated mononuclear cells from patients with asthma, and their contribution to proliferation and survival of eosinophils in vitro. Tacrolimus colony stimulating factor 2 Homo sapiens
3 FK506 inhibited granulocyte/macrophage colony-stimulating factor production by stimulated mononuclear cells from asthma patients at lower concentrations than cyclosporin A. Tacrolimus colony stimulating factor 2 Homo sapiens