Title : Generation of reactive oxygen species by Co(II) from H2O2 in the presence of chelators in relation to DNA damage and 2'-deoxyguanosine hydroxylation.

Pub. Date : 1996 Jan

PMID : 8568912






3 Functional Relationships(s)
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1 Generation of reactive oxygen species by Co(II) from H2O2 in the presence of chelators in relation to DNA damage and 2"-deoxyguanosine hydroxylation. Reactive Oxygen Species mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 The generation of reactive oxygen species by Co(II) from H2O2 in the presence of chelators and related DNA damage was investigated by electron spin resonance (ESR), electrophoretic assays, and high-performance liquid chromatography (HPLC). Reactive Oxygen Species mitochondrially encoded cytochrome c oxidase II Homo sapiens
3 The results indicate that the oxidation potential of Co(II) can be modulated by chelators to facilitate its generation of reactive oxygen species from H2O2. Reactive Oxygen Species mitochondrially encoded cytochrome c oxidase II Homo sapiens