Title : Conformationally constrained analogues of diacylglycerol. 11. Ultrapotent protein kinase C ligands based on a chiral 5-disubstituted tetrahydro-2-furanone template.

Pub. Date : 1996 Jan 5

PMID : 8568819






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Since the interaction of PK-C with DAG is stereospecific, it was anticipated that PK-C would bind tightly to only one enantiomeric form of the compounds constructed with this new lactone template. Lactones proline rich transmembrane protein 2 Homo sapiens
2 Since the interaction of PK-C with DAG is stereospecific, it was anticipated that PK-C would bind tightly to only one enantiomeric form of the compounds constructed with this new lactone template. Lactones proline rich transmembrane protein 2 Homo sapiens