Title : Detection of ret homodimers in MEN 2A-associated pheochromocytomas.

Pub. Date : 1996 Jan 17

PMID : 8561803






1 Functional Relationships(s)
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1 Using transfection of NIH 3T3 cells, we have recently demonstrated that multiple endocrine neoplasia (MEN) 2A mutations activate the c-Ret protein by inducing its disulfide-linked homodimerization on the cell surface. Disulfides ret proto-oncogene Homo sapiens