Title : Choline phosphate and phorbol ester potentiate the mitogenic effect of insulin by competitive mechanisms in NIH 3T3 fibroblasts.

Pub. Date : 1996 Jan 17

PMID : 8561786






2 Functional Relationships(s)
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1 Treatments of serum-starved NIH 3T3 fibroblasts with either 100 nM phorbol-12-myristate 13-acetate (PMA) or 1 mM choline phosphate (ChoP) greatly enhanced, in a mutually inhibitory manner, the stimulatory effect of insulin on DNA synthesis. Tetradecanoylphorbol Acetate insulin Homo sapiens
2 Treatments of serum-starved NIH 3T3 fibroblasts with either 100 nM phorbol-12-myristate 13-acetate (PMA) or 1 mM choline phosphate (ChoP) greatly enhanced, in a mutually inhibitory manner, the stimulatory effect of insulin on DNA synthesis. Tetradecanoylphorbol Acetate insulin Homo sapiens