Title : Thrombin-induced GPIb-IX centralization on the platelet surface requires actin assembly and myosin II activation.

Pub. Date : 1996 Jan 15

PMID : 8555484






1 Functional Relationships(s)
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1 Blockage of cytosolic calcium increases induced by thrombin by loading with the cell permeant calcium chelator Quin-2 AM inhibited GPIb-IX centralization by 70%, but did not prevent its association with the activated cytoskeleton. Quin2-acetoxymethyl ester coagulation factor II, thrombin Homo sapiens