Title : Agents that elevate cAMP inhibit human neutrophil apoptosis.

Pub. Date : 1995 Dec 26

PMID : 8554613






1 Functional Relationships(s)
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1 Neutrophil apoptosis, determined after 20 h in culture using standard criteria and shedding of cell surface CD16 (Fc gamma RIII), is dramatically inhibited, in a concentration-dependent manner, by the cAMP analogs, dibutyryl-cAMP and 8-Br-cAMP, and the adenylyl cyclase activator, forskolin. Colforsin cathelicidin antimicrobial peptide Homo sapiens