Title : Overexpression of Bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo.

Pub. Date : 1996 Jan 15

PMID : 8551333






1 Functional Relationships(s)
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1 Previous studies have demonstrated that overexpression of the proto-oncogene bcl-2 can protect neuron and neuron-like cell lines from growth factor deprivation, calcium ionophores, glutamate excitotoxicity, hypoglycemia, free radicals, and lipid peroxidation. free BCL2 apoptosis regulator Homo sapiens