Title : Heme oxygenase (HO-1): His-132 stabilizes a distal water ligand and assists catalysis.

Pub. Date : 1996 Jan 23

PMID : 8547275






3 Functional Relationships(s)
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1 His-25 and His-132 are the primary candidates for the proximal heme iron ligand in heme oxygenase isozyme-1 (HO-1). Heme heme oxygenase 1 Homo sapiens
2 His-25 and His-132 are the primary candidates for the proximal heme iron ligand in heme oxygenase isozyme-1 (HO-1). Heme heme oxygenase 1 Homo sapiens
3 These results place His-132 close to the iron on the distal side of the heme pocket and indicate that His-132 facilitates, but is not absolutely required for, the catalytic turnover of HO-1. Heme heme oxygenase 1 Homo sapiens