Title : Circumvention of multidrug resistance in neoplastic cells through scavenger receptor mediated drug delivery.

Pub. Date : 1995 Nov 27

PMID : 8521976






2 Functional Relationships(s)
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1 A conjugate of the antineoplastic drug daunomycin (DNM) with maleylated bovine serum albumin (MBSA-DNM) was taken up with high efficiency by a multidrug resistant variant, JD100, of the murine-macrophage tumour cell line, J774A.1, through the scavenger receptors resulting in cessation of DNA synthesis. Daunorubicin albumin Mus musculus
2 A conjugate of the antineoplastic drug daunomycin (DNM) with maleylated bovine serum albumin (MBSA-DNM) was taken up with high efficiency by a multidrug resistant variant, JD100, of the murine-macrophage tumour cell line, J774A.1, through the scavenger receptors resulting in cessation of DNA synthesis. Daunorubicin albumin Mus musculus