Title : Geographical/interracial differences in polymorphic drug oxidation. Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19.

Pub. Date : 1995 Sep

PMID : 8521680






1 Functional Relationships(s)
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1 While CYP2D6 catalyses the metabolism of lipophilic bases only, CYP2C19 is involved in the metabolism of acids (e.g. S-mephenytoin), bases (e.g. imipramine and omeprazole) and neutral drugs (e.g. diazepam). Imipramine cytochrome P450 family 2 subfamily D member 6 Homo sapiens