Title : An interleukin 1 receptor antagonist blocks the IL-1-induced IL-6 paracrine production through a prostaglandin E2-related mechanism in multiple myeloma.

Pub. Date : 1995 Aug

PMID : 8520508






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Indomethacin, a potent inhibitor of cyclo-oxygenase and of PGE2 synthesis, significantly inhibits IL-6 production (but not IL-1 production) by 35% to 90% depending on the different MM patients studied and concurrently to that of PGE2. Indomethacin interleukin 6 Homo sapiens