Pub. Date : 1993 May
PMID : 8518229
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Expression of the endogenous c-myc gene has now been monitored during the differentiation, and associated loss of proliferation, of ML-1 human myeloblastic leukemia cells: c-myc mRNA remains detectable, at decreased levels, during differentiation along the monocyte/macrophage pathway induced with 12-O-tetradecanoylphorbol-13-acetate. | Tetradecanoylphorbol Acetate | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 2 | These findings suggest that, during the 12-O-tetradecanoylphorbol-13-acetate-induced differentiation and loss of proliferation of ML-1 cells, c-myc protein is regulated through alterations that affect its cytoplasmic/nuclear distribution rather than its total cellular content. | Tetradecanoylphorbol Acetate | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |