Title : Induction and suppression of cytokine release (tumour necrosis factor-alpha; interleukin-6, interleukin-1 beta) by Escherichia coli pathogenicity factors (adhesions, alpha-haemolysin).

Pub. Date : 1993 Apr

PMID : 8495969






2 Functional Relationships(s)
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1 Escherichia coli bacteria expressing mannose-resistant fimbriae/haemagglutination induced the production of substantial amounts of tumour necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) from a peripheral human lymphocyte, monocyte, basophil (LMB) cell suspension. Mannose tumor necrosis factor Homo sapiens
2 In this regard, E. coli bacteria with S-mannose-resistant fimbriae/haemagglutination were the most potent inducers of IL-6 and TNF-alpha secretion, followed by the E. coli strain with P-mannose-resistant fimbriae/haemagglutination. Mannose tumor necrosis factor Homo sapiens