Title : Differential effects of the reversible thiol-reactive agents arsenite and methyl methanethiosulfonate on steroid binding by the glucocorticoid receptor.

Pub. Date : 1993 Apr 13

PMID : 8466913






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The vicinally spaced dithiol lies in a region of the receptor that appears to be a contact site for hsp90, which is required for the high-affinity steroid binding conformation of the glucocorticoid receptor [Dalman, F. C., Scherrer, L. C., Taylor, L. P., Akil, H., & Pratt, W. B. Steroids heat shock protein 90 alpha family class A member 1 Homo sapiens