Title : Quaternary salts of 3,3'-bis-pyridinium monooximes: synthesis and biological activity.

Pub. Date : 1993 Mar

PMID : 8450418






1 Functional Relationships(s)
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1 Both the in vitro reactivation potency, in experiments with lyophilized electric eel acetylcholinesterase (AChE) inhibited by diisopropylfluorophosphate, and in vivo protection efficacy against diisopropylfluorophosphate intoxication in mice of these compounds were evaluated and compared with those of trimedoxime and 2-pyridine-aldoxime methiodide. Isoflurophate acetylcholinesterase Mus musculus