Pub. Date : 1993 Mar 15
PMID : 8449916
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Protein kinase C activation without membrane contact in platelets stimulated by bryostatin. | Bryostatins | proline rich transmembrane protein 2 | Homo sapiens |
| 2 | In a cell-free assay, bryostatin-1 activated PKC purified from platelets if the membrane-derived lipid phosphatidyl serine was present; however, if 12(S)-hydroxy-5,8,10,14-eicosatetraenoic acid or arachidonic acid, two lipid products formed in the cytoplasm of activated platelets, were present, no membrane-derived lipids were required for bryostatin-induced PKC activation. | Bryostatins | proline rich transmembrane protein 2 | Homo sapiens |
| 3 | In a cell-free assay, bryostatin-1 activated PKC purified from platelets if the membrane-derived lipid phosphatidyl serine was present; however, if 12(S)-hydroxy-5,8,10,14-eicosatetraenoic acid or arachidonic acid, two lipid products formed in the cytoplasm of activated platelets, were present, no membrane-derived lipids were required for bryostatin-induced PKC activation. | Bryostatins | proline rich transmembrane protein 2 | Homo sapiens |