Title : Formation of 7 alpha- and 7 beta-hydroxylated bile acid precursors from 27-hydroxycholesterol in human liver microsomes and mitochondria.

Pub. Date : 1993 Mar

PMID : 8444412






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Purification and subfractionation of microsomal protein yielded a fraction of cytochrome P-450, which required NADPH and NADPH-cytochrome P-450 reductase and catalyzed 7 alpha-hydroxylation of the side-chain oxygenated 3 beta-hydroxy-delta 5-C27-steroids but was inactive toward cholesterol. NADP cytochrome P450 family 4 subfamily F member 3 Homo sapiens