Pub. Date : 1993 Mar
PMID : 8440921
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Direct interaction of antifungal azole-derivatives with calmodulin: a possible mechanism for their therapeutic activity. | Azoles | calmodulin 1 | Homo sapiens |
| 2 | All azole derivatives tested competitively inhibited calmodulin activity with 50% inhibitory concentration values in the low micromolar range. | Azoles | calmodulin 1 | Homo sapiens |
| 3 | Thus, this study provides evidence that direct interaction with calmodulin might contribute to the therapeutic activity of azole derivatives, particularly to their efficacy in the treatment of inflammatory skin disorders. | Azoles | calmodulin 1 | Homo sapiens |