Pub. Date : 1993 Feb 15
PMID : 8432975
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | After a longer, 20-h treatment with PMA (20 nM), a considerable portion of PKC was still membrane-associated, and the total amount of immunoreactive PKC was not reduced considerably. | Tetradecanoylphorbol Acetate | protein kinase C alpha | Homo sapiens |
| 2 | After a longer, 20-h treatment with PMA (20 nM), a considerable portion of PKC was still membrane-associated, and the total amount of immunoreactive PKC was not reduced considerably. | Tetradecanoylphorbol Acetate | protein kinase C alpha | Homo sapiens |
| 3 | We propose that Bryo inhibits PMA-induced T cell proliferation by causing rapid degradation of PKC, reflecting a requirement of persistent PKC stimulation (lasting approximately 48 h) for the activation of human T cells and progression through the cell cycle. | Tetradecanoylphorbol Acetate | protein kinase C alpha | Homo sapiens |